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. 2016 Feb 19;7(12):14940–14950. doi: 10.18632/oncotarget.7496

Figure 4. The combined therapy of VNP-shABCB5 with CTX delayed tumor growth and enhanced survival time in B16F10 mice model.

Figure 4

A. Tumor growth curves. Tumor-bearing mice were injected i.p. with PBS, CTX, VNP-scrambled plus CTX, VNP-shABCB5 plus CTX (n = 9, each group). Tumor volumes among different groups were compared. Data are presented as mean ± SD. *, P < 0.05. B. Kaplan-Meier survival curves of mice bearing B16F10 melanomas. Data were analyzed by the log-rank test. *, P < 0.05. C. Tumor doubling time. Data are presented as mean ± SD. *, P < 0.05.