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. 2016 Feb 25;7(12):14983–15017. doi: 10.18632/oncotarget.7698

Table 1. Body and liver weights after diclofenac treatment.

Duration Dosage Body weight (g) Liver weight (g)
Before administration After administration Absolute weight (g) Relative ratio (%)
Day 1 Vehicle 22.86 ± 1.64 23.63 ± 1.24 1.13 ± 0.03 4.77 ± 0.18 (100)
30 mg/kg 21.16 ± 1.11 20.90 ± 0.14 1.08 ± 0.03 5.14 ± 0.12a (108)
Day 3 Vehicle 20.68 ± 0.86 22.48 ± 0.43b 1.13 ± 0.03 5.02 ± 0.08 (100)
30 mg/kg 22.02 ± 1.02 22.84 ± 0.54 1.21 ± 0.03a 5.31 ± 0.25 (106)
Day 14 Vehicle 24.62 ± 1.03 21.01 ± 1.22c 0.92 ± 0.13 4.41 ± 0.72 (100)
30 mg/kg 24.80 ± 0.83 20.43 ± 0.84c 1.05 ± 0.06 5.14 ± 0.18 (117)

Values represent the means ± standard deviation (SD). The relative organ weight was calculated using the ratio of liver weight to body weight and is represented as a percentage of the total body weight.

P-values were calculated using the Student's t-test and significance is defined by

a

P < 0.05; vs. corresponding control vehicle.

b

P < 0.05; vs. corresponding before administration;

c

P < 0.01; vs. corresponding before administration.