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. 2016 Mar 3;7(12):15105–15117. doi: 10.18632/oncotarget.7874

Figure 3. Apoptotic death in the small intestine with radiation-induced small intestinal injury.

Figure 3

Apoptotic death was defined as the average number and density of terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL)-positive cells in 10 random fields from each section at 400× magnification (A). Signals density for TUNEL-positive cells was measured in the marked areas (arrow, edge of the villi. arrowhead, the muscularis mucosa). Each bar represents the mean ± standard error (SE); *p < 0.05 indicates differences between the radiation (RT) and alpha-lipoic acid (ALA) + RT groups (B). Con: control group; RT: radiation group; ALA + RT: received ALA before irradiation. Scale bar; 100 μm. Con and ALA (n = 4/each day), RT and ALA + RT (n = 10/each day).