Table 3. Correlation between OPG expression and clinicopathological characteristics of patients with CRC.
| Characteristics | Number of cases (%) | P-value | |
|---|---|---|---|
| Reduced | Preserved | ||
| Age (years) | |||
| ≥ 61 | 41 (68.3) | 19 (31.7) | 0.992 |
| < 61 | 39 (68.4) | 18 (31.6) | |
| Gender | |||
| Man | 54 (70.1) | 23 (29.9) | 0.571 |
| Woman | 26 (65.0) | 14 (35.0) | |
| Size of primary tumor | |||
| ≥ 5 cm | 52 (82.5) | 11 (17.5) | 0.001 |
| < 5 cm | 28 (51.9) | 26 (48.1) | |
| Size of metastatic tumor | |||
| ≥ 3 cm | 31 (100.0) | 0 (0.0) | 0.001 |
| < 3 cm | 26 (70.3) | 11 (29.7) | |
| Histologic grade | |||
| 3 | 3 (100.0) | 0 (0.0) | < 0.001 |
| 2 | 72 (73.5) | 26 (26.5) | |
| 1 | 5 (31.3) | 11 (68.8) | |
| Pathological tumor stage | |||
| pT4 | 11 (91.7) | 1 (8.3) | 0.100 |
| pT3 | 69 (65.7) | 36 (34.3) | |
| Nodal metastasis | |||
| Present | 42 (85.7) | 7 (14.3) | 0.001 |
| Absent | 38 (55.9) | 30 (44.1) | |
| First hepatic metastasis | |||
| Present | 57 (83.8) | 11 (16.2) | < 0.001 |
| Absent | 23 (46.9) | 26 (53.1) | |
| Recurrent hepatic metastasis | |||
| Present | 40 (90.9) | 4 (9.1) | 0.043 |
| Absent | 17 (70.8) | 7 (29.2) | |
| Stage group | |||
| IV | 31 (77.5) | 9 (22.5) | 0.003 |
| III | 19 (100.0) | 0 (0.0) | |
| II | 30 (51.7) | 28 (48.3) | |
| Lymphatic invasion | |||
| Present | 22 (81.5) | 5 (18.5) | 0.105 |
| Absent | 58 (64.4) | 32 (35.6) | |
| Vascular invasion | |||
| Present | 12 (100.0) | 0 (0.0) | 0.009 |
| Absent | 68 (64.8) | 37 (35.2) | |
The results highlighted in bold represent statistically significant values (P < 0.05).