Table 1. Univariate Cox proportional hazards regression models of prognostic factors associated with overall survival (OS) and disease-free survival (DFS) in cervical cancer patients.
| Variable | OS | DFS | |||
|---|---|---|---|---|---|
| HR (95%CI) | P-value | HR (95%CI) | p-value | ||
| Parturition | 1.369 (0.917-2.045) | 0.124 | 1.412 (0.946-2.107) | 0.091 | |
| Age | <48 | 1 | 1 | ||
| ≥48 | 1.090 (0.733-1.619) | 0.671 | 1.097 (0.738-1.630) | 0.648 | |
| NLR | <2.77 | 1 | 1 | ||
| ≥2.77 | 1.480 (0.995-2.201) | 0.053 | 1.481 (0.997-2.201) | 0.052 | |
| PLR | <128.3 | 1 | 1 | ||
| ≥128.3 | 1.746 (1.165-2.617) | 0.007 | 1.767 (1.179-2.649) | 0.006 | |
| LMR | <2.41 | 1 | 1 | ||
| ≥2.41 | 0.631 (0.392-1.014) | 0.057 | 0.617 (0.384-0.993) | 0.047 | |
| Albumin | <43.65 | 1 | |||
| ≥43.65 | 0.519 (0.348-0.773) | 0.001 | 0.511 (0.343-0.761) | 0.001 | |
| FIGO Stage | IA | 1 | 1 | ||
| IB | 3.807 (1.176-12.321) | 0.026 | 3.918 (1.211-12.679) | 0.023 | |
| IIA | 5.524 (1.727-17.665) | 0.004 | 5.944 (1.859-19.000) | 0.003 | |
| Differentiation | Well | 1 | 1 | ||
| Mod. | 3.969 (1.429-11.028) | 0.008 | 3.913 (1.409-10.872) | 0.009 | |
| Poorly | 7.337 (2.644-20.357) | <0.001 | 7.268 (2.620-20.157) | <0.001 | |
| PLN | No | 1 | 1 | ||
| Yes | 3.104 (2.025-4.759) | <0.001 | 3.259 (2.127-4.992) | <0.001 | |
| LVSI | No | 1 | |||
| Yes | 1.821 (1.170-2.836) | 0.008 | 1.887 (1.212-2.938) | 0.005 | |
| Histological | Squ | ||||
| Non-S | 0.982 (0.600-1.607) | 0.942 | 0.953 (0.583-1.559) | 0.848 | |
| SIS | 0 | 1 | |||
| 1 | 1.987 (1.153-3.423) | 0.013 | 1.967 (1.142-3.386) | 0.015 | |
| 2 | 3.187 (1.793-5.664) | <0.001 | 3.290 (1.852-5.843) | <0.001 |
PLR: platelet-lymphocyte ratio, NLR: neutrophil-lymphocyte ratio, LMR: lymphocyte-monocyte ratio, PLN: pelvic lymph node metastasis, LVSI: vascular lymph node invasion