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. Author manuscript; available in PMC: 2016 Jun 28.
Published in final edited form as: Neuroscientist. 2014 Apr 11;20(5):483–498. doi: 10.1177/1073858414529829

Figure 9.

Figure 9

Driving forces for homosynaptic and heterosynaptic weight changes. Homosynaptic plasticity, LTP or LTD, is induced only at synapses active during the induction, and requires specific activity patterns. Homosynaptic LTP leads to weight-dependent increase of synaptic weights: potentiation is stronger at initially weak than at initially strong synapses. Homosynaptic LTD leads to weight-dependent decrease of synaptic weights: depression of strong synapses is stronger than depression of the weak synapses. Heterosynaptic plasticity can be induced at any synapse during episodes of strong postsynaptic activity. Initially weak synapses are subject to weight-dependent heterosynaptic LTP. Initially strong synapses are subject to weight-dependent heterosynaptic LTD.