Dependence of detection time and probability on the signal amplitude and the firing rate. (A, B) Probability of detection of artificial excitatory postsynaptic current (EPSC) versus time after the artificial EPSC (aEPSC) onset for population of N = 1000 neurons, for different amplitudes of aEPSCs (A, mean firing rate 5 Hz) and different firing rate of transmitting neurons (B, aEPSC amplitude 50 pA), as indicated. Data from one layer 2/3 pyramidal neuron (Ilin, Stevenson, Volgushev, unpublished).