Table 2. Potential risk factors of VTE for patients with musculoskeletal tumors around the knee with multivariate cox regression analyses.
| Patients (No) | VTE (n,%) | B | SE | Wald | Sig | Exp (B) | |
|---|---|---|---|---|---|---|---|
| Demographic data | |||||||
| Age<60y | 255 | 53 (21.2%) | -0.371 | 0.177 | 4.414 | 0.055 | 0.690 |
| Age>60y | 53 | 14 (26.4%) | |||||
| Female | 168 | 37 (22.0%) | -0.127 | 0.134 | 0.903 | 0.342 | 0.880 |
| Male | 140 | 30 (21.4%) | |||||
| BMI<25kg/m2 | 284 | 60 (21.1%) | 0.269 | 0.263 | 1.264 | 0.261 | 1.344 |
| BMI>25kg/m2 | 24 | 7 (29.1%) | |||||
| Tumour history | |||||||
| Benign | 128 | 23 (18.0%) | 0.262 | 0.524 | 0.249 | 0.618 | 1.299 |
| Malignant | 180 | 44 (24.4%) | |||||
| Bone tumor | 82 | 17 (20.7%) | 0.132 | 0.151 | 0.767 | 0.381 | 1.141 |
| Soft tissue tumor | 226 | 50 (22.1%) | |||||
| Primary | 270 | 55 (20.4%) | 0.033 | 0.199 | 0.028 | 0.867 | 1.034 |
| Metastasis | 38 | 11 (29.0%) | |||||
| Pathological fracture | 27 | 7 (26.0%) | 0.089 | 0.260 | 0.117 | 0.732 | 1.093 |
| Non-pathological fracture | 281 | 60 (20.0%) | |||||
| Location | |||||||
| Distal femur | 232 | 54 (23.3%) | 0.009 | 0.149 | 0.004 | 0.952 | 1.009 |
| Proximal tibia | 72 | 12 (16.7%) | |||||
| Total knee joint | 4 | 1 (25.0%) | |||||
| Chemotherapy | |||||||
| Yes | 175 | 40 (22.9%) | -0.150 | 0.530 | 0.081 | 0.776 | 0.860 |
| No | 133 | 27 (20.3%) | |||||
| Radiotherapy | |||||||
| Yes | 84 | 21 (25.0%) | -0.110 | 0.179 | 0.375 | 0.540 | 0.896 |
| No | 224 | 46 (20.5%) |
VTE includes symptomatic/asymptomatic deep venous thrombosis, symptomatic pulmonary embolism; DVT includes symptomatic/asymptomatic deep venous thrombosis.