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. 2016 Jul;148(1):1–11. doi: 10.1085/jgp.201511538

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© 2016 Frederiksen et al.

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Figure 4. — Time course of rhodopsin regeneration. Rhodopsin regeneration measured as normalized OD at 500 nm after completion of Meta III decay in WT (n = 5), Grk1^−/− (n = 5), and Arr1^−/− (n = 7) mouse rods after 70% pigment bleaching and exogenous treatment with 10 µM 11-cis retinal. Fitting with single saturation exponential functions yielded regeneration time constants (τ ± SEM) of 8.4 ± 0.4 min (WT), 7.0 ± 0.4 min (Grk1^−/−), and 8.2 ± 0.8 min (Arr1^−/−). Error bars represent SEM in all panels. All recordings were made at 27°C.