Abstract
Sixty-six elderly subjects (mean age 77 years) whose mental state was assessed clinically and by simple psychometric tests have been studied by computerised tomography. The mean maximum ventricular area in the 17 mentally normal subjects was above the upper limit of normal for younger subjects, and there was a broad relationship between increasing ventricular dilatation and increasing intellectual impairment. No such clear relationship was demonstrable for measures of cortical atrophy.
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- BURHENNE H. J., DAVIES H. THE VENTRICULAR SPAN IN CEREBRAL PNEUMOGRAPHY. Am J Roentgenol Radium Ther Nucl Med. 1963 Dec;90:1176–1184. [PubMed] [Google Scholar]
- ENGESET A., LONNUM A. Third ventricles of 12 mm width or more: a preliminary report. Acta radiol. 1958 Jul-Aug;50(1-2):5–11. doi: 10.3109/00016925809171061. [DOI] [PubMed] [Google Scholar]
- Fox J. H., Topel J. L., Huckman M. S. Use of computerized tomography in senile dementia. J Neurol Neurosurg Psychiatry. 1975 Oct;38(10):948–953. doi: 10.1136/jnnp.38.10.948. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GOSLING R. H. The association of dementia with radiologically demonstrated cerebral atrophy. J Neurol Neurosurg Psychiatry. 1955 May;18(2):129–133. doi: 10.1136/jnnp.18.2.129. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gawler J., Du Boulay G. H., Bull J. W., Marshall J. Computerized tomography (the EMI Scanner): a comparison with pneumoencephalography and ventriculography. J Neurol Neurosurg Psychiatry. 1976 Mar;39(3):203–211. doi: 10.1136/jnnp.39.3.203. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Godber C. The physician and the confused elderly patient. J R Coll Physicians Lond. 1975 Oct;10(1):101–112. [PMC free article] [PubMed] [Google Scholar]
- Gyldensted C., Kosteljanetz M. Measurements of the normal hemispheric sulci with computer tomography: a preliminary study on 44 adults. Neuroradiology. 1975 Dec 19;10(3):147–149. doi: 10.1007/BF00341816. [DOI] [PubMed] [Google Scholar]
- Gyldensted C., Kosteljanetz M. Measurements of the normal ventricular system with computer tomography of the brain. A preliminary study on 44 adults. Neuroradiology. 1976;10(4):205–213. doi: 10.1007/BF00329997. [DOI] [PubMed] [Google Scholar]
- Huckman M. S., Fox J., Topel J. The validity of criteria for the evaluation of cerebral atrophy by computed tomography. Radiology. 1975 Jul;116(1):85–92. doi: 10.1148/116.1.85. [DOI] [PubMed] [Google Scholar]
- Nielsen R., Petersen O., Thygesen P., Willanger R. Encephalographic ventricular atrophy. Relationships between size of ventricular system and intellectual impairment. Acta Radiol Diagn (Stockh) 1966 May;4(3):240–256. doi: 10.1177/028418516600400302. [DOI] [PubMed] [Google Scholar]
- ROBINSON R. A. Some problems of clinical trials in elderly people. Gerontol Clin (Basel) 1961;3:247–257. doi: 10.1159/000244693. [DOI] [PubMed] [Google Scholar]
- ROTH M., HOPKINS B. Psychological test performance in patients over sixty. I. Senile psychosis and the affective disorders of old age. J Ment Sci. 1953 Jul;99(416):439–450. doi: 10.1192/bjp.99.416.439. [DOI] [PubMed] [Google Scholar]
- Roberts M. A., Caird F. I., Grossart K. W., Steven J. L. Computerized tomography in the diagnosis of cerebral atrophy. J Neurol Neurosurg Psychiatry. 1976 Sep;39(9):909–915. doi: 10.1136/jnnp.39.9.909. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tomlinson B. E., Blessed G., Roth M. Observations on the brains of non-demented old people. J Neurol Sci. 1968 Sep-Oct;7(2):331–356. doi: 10.1016/0022-510x(68)90154-8. [DOI] [PubMed] [Google Scholar]
- Willanger R., Thygesen P., Nielsen R., Petersen O. Intellectual impairment and cerebral atrophy. A psychological, neurological and radiological investigation. Dan Med Bull. 1968 Mar;15(3):65–93. [PubMed] [Google Scholar]