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. 2016 Jun 27;213(7):1175–1183. doi: 10.1084/jem.20151966

Figure 2.

Figure 2.

VEGF maintains hyaloid vessels via endothelial VEGFR2. (A–C) Whole-mount stained images of hyaloid vessels at P6 and quantification (n = 4). (D–I) Whole-mount stained images of hyaloid vessels at P6. Neither Vegfr1 nor Vegfr2 is detected in macrophages (arrowheads in G and I). (J and K) Schematic diagram depicting the timing of 4-hydroxytamoxifen (4OHT) injections. (L–S) Whole-mount stained images of hyaloid vessels at P6 and quantification (n = 4). Bars: (D–F and N–Q) 500 µm; (A, B, G–I, L, and M) 50 µm. *, P < 0.05; **, P < 0.01; two-tailed Student’s t tests. Representative confocal images from four independent experiments (four mice per group) are shown. Data are represented as mean ± SD. CAT, chloramphenicol acetyltransferase; Cont, control.