A and B: Growth curves of wild-type and Lztfl1 knockout mice. A:
Lztfl1 knockout mice weighed less than their wild-type counterparts at birth, but reached similar weight to wild-type mice by approximately 10 weeks of age. Data are shown as mean ± SEM, P < 0.01. B:
Lztfl1 knockout mice gained more weight than their wild-type counterparts over their lifetimes. Wild-type and Lztfl1 knockout mice were weighed at all ages. The curves were plotted using non-linear regression method with statistical correlation analysis, P < 0.01. C and D: Comparison of wild-type and Lztfl1 knockout mice at different ages. WT, wild-type; KO, knockout.