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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Pediatr. 2016 Apr 19;174:98–103.e1. doi: 10.1016/j.jpeds.2016.03.035

Table 3.

Seizure management among 426 neonates with clinically suspected and/or EEG confirmed seizures who were monitored by cEEG.

Overall N=426
Initial loading medication and dose
 Phenobarbital (20mg/kg, IQR 20, 20mg/kg) 379 (89%)
 Levetiracetam (20mg/kg, IQR 20, 32mg/kg) 22 (5%)
 Fosphenytoin (20m/kg, IQR 15, 20mg/kg) 4 (1%)
 No loading dose 18 (4%)
Seizure medications administered during the admission
 Phenobarbital 393 (92%)
 Levetiracetam 134 (31%)
 Fosphenytoin 119 (28%)
 Benzodiazepine – intermittent doses 84 (20%)
 Benzodiazepine infusion 31 (7%)
 Topiramate 17 (4%)
 Carbamazepine/oxcarbazepine 9 (2%)
 Vitamin(s): (pyridoxine, folic acid, pyridoxal 5 phosphate) 32 (8%)
Number of anti-seizure medications administered
 0 10 (2%)
 1 194 (46%)
 2 101 (24%)
 3 68 (16%)
 ≥4 53 (12%)