Table 3.
Seizure management among 426 neonates with clinically suspected and/or EEG confirmed seizures who were monitored by cEEG.
| Overall N=426 | |
|---|---|
| Initial loading medication and dose | |
| Phenobarbital (20mg/kg, IQR 20, 20mg/kg) | 379 (89%) |
| Levetiracetam (20mg/kg, IQR 20, 32mg/kg) | 22 (5%) |
| Fosphenytoin (20m/kg, IQR 15, 20mg/kg) | 4 (1%) |
| No loading dose | 18 (4%) |
| Seizure medications administered during the admission | |
| Phenobarbital | 393 (92%) |
| Levetiracetam | 134 (31%) |
| Fosphenytoin | 119 (28%) |
| Benzodiazepine – intermittent doses | 84 (20%) |
| Benzodiazepine infusion | 31 (7%) |
| Topiramate | 17 (4%) |
| Carbamazepine/oxcarbazepine | 9 (2%) |
| Vitamin(s): (pyridoxine, folic acid, pyridoxal 5 phosphate) | 32 (8%) |
| Number of anti-seizure medications administered | |
| 0 | 10 (2%) |
| 1 | 194 (46%) |
| 2 | 101 (24%) |
| 3 | 68 (16%) |
| ≥4 | 53 (12%) |