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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: J Neurovirol. 2016 Jan 4;22(4):479–487. doi: 10.1007/s13365-015-0416-1

Fig 2.

Fig 2

Caption Longitudinal effect of detectable CSF HIV RNA (≥50 copies/ml) on Beck Depression Inventory (BDIa) scores using adjustedb linear mixed models with random intercept in persons without depression (DSM IV criteria) at baseline.

Annotation Change in depression (BDI) scores represents the longitudinal change in BDI scores from baseline with reference to persons without detectable CSF HIV RNA. *P<0.05

aDepression assessed by Beck depression inventory II (BDI); depression severity scores: 0–9, minimal; 10–16, mild; 17–29, moderate; 30–63, severe.

bMultivariate linear mixed model adjusted for log plasma HIV RNA, race, age, sex, education, nadir and current CD4 counts, CNS Penetration Effectiveness score (CPE), lifetime depression diagnosis, depression at prior study visit, years infected with HIV, cognitive impairment (global deficit score-GDS), and prior diagnosis of HCV infection.