Table IV.

Patient characteristics and neurodevelopmental outcomes for patients without a genetic anomaly by hypoglycemia status^*

	Moderate to severe hypoglycemia (N = 8)	No to mild hypoglycemia (N = 159)	P value†
Patient characteristics
Age at surgery, mo	1.7 ± 3.7	3.1 ± 2.8	.18
≤60 days	7 (88)	67 (42)	.02
RACHS-1 category ≥3 or not assignable	8 (100)	84 (53)	.009
Single ventricle physiology	1 (13)	37 (23)	.68
Premature birth (<37 weeks)	3 (38)	15 (9)	.04
Maternal education: high school diploma or lower‡	1 (13)	50 (32)	.44
Duration of cardiopulmonary bypass ≥ 150 minutes	2 (25)	29 (18)	.63
Deep hypothermic circulatory arrest	1 (13)	35 (22)	.69
Delayed sternal closure	1 (13)	22 (14)	1.0
Tight glycemic control group	7 (88)	74 (47)	.03
Cardiac ICU duration of stay, d			.02
<2	0	45 (28)
2-4.99	2 (25)	62 (39)
≥5	6 (75)	52 (33)
Bayley-III scores
Age at testing, mo	14.2 ± 2.7	13.3 ± 1.8	.04
Composite scores
Cognitive	95.0 ± 10.7	104.7 ± 11.5	.02
Language§	86.5 ± 16.5	97.7 ± 11.6	.009
Motor	82.4 ± 14.4	92.8 ± 13.3	.03
Subscale scores
Cognitive	9.0 ± 2.1	10.9 ± 2.3	.02
Receptive communication§	7.9 ± 3.2	9.9 ± 2.2	.01
Expressive communication§	7.4 ± 2.5	9.3 ± 2.3	.02
Fine motor	7.9 ± 1.8	9.8 ± 2.4	.02
Gross motor	6.3 ± 3.5	7.7 ± 3.0	.17

^*Values are mean ± SD or n (%).

^†P values for the comparison between groups were calculated with the use of linear regression or stratified exact tests with adjustment for site, as appropriate.

^‡Maternal education not available for 3 patients with no to mild hypoglycemia.

^§Bayley-III language composite score and receptive and expressive communication subscale scores were not available for 1 patient with no to mild hypoglycemia.