Table V.

Multivariable regression to evaluate the impact of hypoglycemia status and other factors on neurodevelopmental outcomes in patients without a genetic anomaly (N = 167)

Bayley-III composite score	Covariates	Beta coefficient (95% CI)	P value*
Cognitive	Moderate to severe hypoglycemia	–9.6 (–17.8 to –1.3)	.02
Language†	Moderate to severe hypoglycemia	–9.3 (–17.7 to –1.0)	.03
	Maternal education: high school diploma or lower	–4.0 (–7.9 to –0.2)	.04
	Cardiac ICU duration of stay, d
	<2	Reference
	2-4.99	–2.6 (–7.0 to 1.9)	.26
	≥5	–7.8 (–12.5 to –3.0)	.002
Motor	Moderate to severe hypoglycemia	–11.8 (–21.0 to –2.6)	.01
	Age ≤60 days	11.5 (6.7 to 16.3)	<.001
	RACHS-1 category ≥3 or not assignable	–8.6 (–13.3 to –3.9)	<.001
	Delayed sternal closure	–7.3 (–13.2 to –1.3)	.02

^*P values were calculated with the use of multivariable linear regression with adjustment for site. Coefficients for intercept and site are not reported.

^†N = 164. Maternal education was not available for 3 patients with no to mild hypoglycemia, including one patient for whom the Bayley-III language composite score was not available.