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. 2016 Jun 29;7:191. doi: 10.3389/fphar.2016.00191

Figure 4.

Figure 4

Anti-angiogenic effect of icariin and its derivatives. The treatment of icariin, icaritin, and icariside II have resulted in anti-angiogenic effect. This can be due to the reduction in expression of VEGF, a crucial growth factor that acts as the fundamental regulator of angiogenesis.