Table 3.
Adverse events and post-procedural characteristics of Child-Pugh B (7/8) patients with HCC treated with MW ablation vs. IRE
| MW (N = 25) | IRE (N = 30) | P-Value | |
|---|---|---|---|
| Intra-operative complications | |||
| Arrhythmia | 0 | 0 | NS |
| High Current | 0 | 2 | 0.10 |
| Failure to deliver | 0 | 0 | NS |
| Length of stay (days; median, range) | 2 (1–5) | 1 (1–4) | 0.05 |
| 30 day tolerance (median, range) | |||
| AST (fold increase) | 2 (1–4) | 0 (1–2) | 0.05 |
| ALT | 2 (1–4) | 0 (1–2) | 0.05 |
| Total bilirubin | 1.5 (1–2) | 1 (1–1) | 0.07 |
| Increased ascites | 13 (52%) | 5 (16%) | 0.02 |
| 90 day tolerance (median, range) | |||
| AST (fold increase) | 1 (1–4) | 0 (1–2) | 0.09 |
| ALT | 1(1–4) | 0 (1–2) | 0.09 |
| Total bilirubin | 0 (1–2) | 0 (0–1) | 0.12 |
| Increased ascites | 5 (20%) | 2 (6%) | 0.05 |
| Pleural effusion (90 day) | 14 | 5 | <0.01 |
| Portal vein thrombosis (90 day) | 5 | 1 | 0.03 |
| Readmission (90 day) | 9 (36%) | 4 (13%) | 0.03 |
| Reasons for readmission | |||
| Uncontrolled ascites | 4 (all grade III) | 1 (grade II) | 0.11 |
| Dehydration | 2 (all grade II) | 1 (grade II) | 0.46 |
| Liver failure | 5 (four grade II, one grade III) | 2 (all grade II) | 0.14 |
| Ablation success | |||
| 90 day | 25 (100%) | 30 (100%) | NS |
| 180 day | 25 (100%) | 29 (97%) | 0.37 |