Table 3.
Adverse events and post-procedural characteristics of Child-Pugh B (7/8) patients with HCC treated with MW ablation vs. IRE
MW (N = 25) | IRE (N = 30) | P-Value | |
---|---|---|---|
Intra-operative complications | |||
Arrhythmia | 0 | 0 | NS |
High Current | 0 | 2 | 0.10 |
Failure to deliver | 0 | 0 | NS |
Length of stay (days; median, range) | 2 (1–5) | 1 (1–4) | 0.05 |
30 day tolerance (median, range) | |||
AST (fold increase) | 2 (1–4) | 0 (1–2) | 0.05 |
ALT | 2 (1–4) | 0 (1–2) | 0.05 |
Total bilirubin | 1.5 (1–2) | 1 (1–1) | 0.07 |
Increased ascites | 13 (52%) | 5 (16%) | 0.02 |
90 day tolerance (median, range) | |||
AST (fold increase) | 1 (1–4) | 0 (1–2) | 0.09 |
ALT | 1(1–4) | 0 (1–2) | 0.09 |
Total bilirubin | 0 (1–2) | 0 (0–1) | 0.12 |
Increased ascites | 5 (20%) | 2 (6%) | 0.05 |
Pleural effusion (90 day) | 14 | 5 | <0.01 |
Portal vein thrombosis (90 day) | 5 | 1 | 0.03 |
Readmission (90 day) | 9 (36%) | 4 (13%) | 0.03 |
Reasons for readmission | |||
Uncontrolled ascites | 4 (all grade III) | 1 (grade II) | 0.11 |
Dehydration | 2 (all grade II) | 1 (grade II) | 0.46 |
Liver failure | 5 (four grade II, one grade III) | 2 (all grade II) | 0.14 |
Ablation success | |||
90 day | 25 (100%) | 30 (100%) | NS |
180 day | 25 (100%) | 29 (97%) | 0.37 |