Table 4. Partial correlation controlling for group coefficients between selected variables included in the study.
| Control Variables | NORTDI | EPM Time open arms | OFT Locomotor activity | Amyloidplaques | SOD1 | 4-HNE | DNMT1 | HDAC2 |
|---|---|---|---|---|---|---|---|---|
| NORT (DI) | 1.000 | −0.251 | 0.238 | −0.485*** | −0.155 | 0.241 | 0.344 | 0.469* |
| EPM Time open arms | 1.000 | −0.208 | 0.480*** | 0.327 | 0.330 | −0.388 | −0.392 | |
| OFT Locomotor activity | 1.000 | −0.424* | −0.308 | −0.427* | 0.096 | 0.368 | ||
| Amyloid plaques | 1.000 | 0.721*** | 0.005 | 0.633** | −0.750*** | |||
| SOD1 | 1.000 | 0.442* | −0.361 | −0.714*** | ||||
| 4-HNE | 1.000 | 0.402 | −0.198 | |||||
| DNMT1 | 1.000 | 0.456* | ||||||
| HDAC2 | 1.000 |
The values used to calculate Partial correlation controlling for group coefficients were Amyloid pathology obtained with S-Thioflavin staining (showed in Figure 7B); behavioral parameters from NORT, EPM and OFT (showed in Figures 1A, 2A and 3C); protein expression for SOD1 and 4-HNE (showed in Figure 5A and 5B); and gene expression for Dnmt1 and Hdac2 (showed in Figures 8C and 9D) Correlation(2-tailed) is significant * p<0.05; **p<0.01 and ***p<0.001; (−) Negative covariation of two variables.