Table 1. Mean (standard deviation) of physical function and body weight of male and female LCR rats by treatment assignment at study entry.
| Male (age 20-22 months) | Female (age 16-18 months) | |||||
|---|---|---|---|---|---|---|
| Outcome Measures | Overall (n=12) | Rapa.-treated (n=6) | Placebo (n=6) | Overall (n=16) | Rapa.-treated (n=8) | Placebo (n=8) |
| Grip strength (g) | 1418 (227) | 1442 (278) | 1394 (185) | 1338 (160) | 1322 (139) | 1355 (187) |
| Adjusted Grip Strength (g/100g weight) | 239 (39) | 244 (37) | 233 (43) | 406 (65) | 398 (59) | 413 (74) |
| MRD (m) | 41.8 (31.4) | 50.0 (35.2) | 33.6 (27.7) | 128.5 (28.6) | 138 (25) | 119 (30) |
| Adjusted MRD Ln(m/100g weight) | 1.64 (0.98) | 1.90 (0.87) | 1.39 (1.09) | 3.63 (0.30) | 3.71 (0.28) | 3.56 (0.31) |
| Body Weight (g) | 600.4 (82.4) | 590.7 (66.2) | 610.2 (101.5) | 335.3 (47.4) | 338.9 (58.8) | 331.8 (36.4) |
Rapa: rapamycin; MRD: Maximum running distance; Ln: natural logarithm