Table 2. Antiepileptic Drugs that Induce Cerebellar Ataxia1.
| 1a – Overview of all of the case and cohort studies found in the literature and included in the present review, percentage of affected patients 1b – Data on ataxia described as an adverse reaction in randomized placebo-controlled studies, percentage of affected patients | ||
|---|---|---|
| 1a | 1b | |
| Clobazam | 6.3% | |
| Clonazepam | 50% | |
| Eslicarbazepine | 7.5% | |
| Gabapentin | 8.7% | 10.1% |
| Lacosamide | 9.3% | |
| Lamotrigine | 5.5% | 18.5% |
| Levetiracetam | 1.5% | |
| Oxcarbazepine | 29.9% | |
| Phenytoin | 37.9% | |
| Pregabalin | 9.7% | |
| Retigabine | 15% | 10.4% |
| Tiagabine | 7.2% | 6.1% |
| Topiramate | 1.3% | 6.6% |
| Valproate | 3.6% | 3% |
| Vigabatrin | 6.8% | 3.6% |
| Zonisamide | 10.6% | 12.7% |
1
Data from (60).