Table 2.
Subsets of inflammatory cells in skin samples from controls and trombiculid and sarcoptic mange-infected chamois.
| Examined subjects | Classification of sarcoptic mange skin lesions | CD3+ lymphocytes/10,000 μm2 | CD79α + lymphocytes/10,000 μm2 | CD68+ macrophages/10,000 μm2 | Eosinophils/10,000 μm2 | Mast cells/10,000 μm2 |
|---|---|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | ||
| Controls | 5.4 ± 4.8 | 1.3 ± 1.9 | 5.0 ± 4.0 | 0.9 ± 1.7 | 0.1 ± 0.3 | |
| Trombiculosis | 10.6 ± 7.1∗ | 2.9 ± 3.0† | 13.0 ± 11.7+ | 5.5 ± 3.8# | 0.3 ± 0.4 | |
| Sarcoptic mange | Grade 1 | 14.1 ± 7.5 | 2.3 ± 2.3 | 16.5 ± 10.0 | 4.0 ± 2.4 | 0.9 ± 0.7 |
| Grade 2 | 15.2 ± 7.6 | 2.4 ± 2.4 | 15.2 ± 10.1 | 7.8 ± 6.8††† | 1.0 ± 0.6 | |
| Grade 3 | 16.7 ± 10.3 | 3.3 ± 3.0∗∗∗ | 16.9 ± 9.2 | 6.2 ± 3.8‡‡‡ | 1.0 ± 0.6 | |
| Total | 15.7 ± 8.9∗‡ | 2.9 ± 2.8† | 16.2 ± 9.7+†† | 6.5 ± 5.2# | 1.0 ± 0.7∗∗‡‡ |
Significant differences among CD3+ T lymphocyte (∗), CD79α + B lymphocyte (†), CD68+ macrophages (+), eosinophils (#) and mast cells (∗∗) with controls. Significant differences between CD3+ T lymphocyte (‡), CD68+ macrophages (††) and mast cells (‡‡) in chamois with sarcoptic mange and subjects with trombiculosis. Significant differences among CD79α + B lymphocyte (∗∗∗) in chamois with grade 3 and subjects with grade 1 and 2; significant differences among eosinophils (†††) in chamois with grade 2 and animals with grade 1 and 3; significant differences between eosinophils (‡‡‡) in chamois with grade 3 and grade 1.