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Representative immunohistochemistry for F4/80 (A) and CD68 (C) in the kidney. Scale bar = 50 μm. Arrows indicate positive staining cells. Bar graph summarizing the F4/80 (B) and CD68 (D)-positive cells in interstitial lesions. Data are means ± SEM; n = 4 in each group. *P < 0.01. Two-way ANOVA, gene, p < 0.001; diet, p < 0.001; gene × diet, p < 0.05.
