Table 2. GeoMean of inhibitor-treated erythrocytes.
| Test | Compounds (24 h incubation) |
2.5 h incubation | Blood Groups | |||
|---|---|---|---|---|---|---|
| DMSO 0.2% (v/v) | Bay 11–7082 (20 μM) | Parthenolide (50 μM) | DMF (140 μM) | Ionomycin (0.25 μM) | ||
| GeoMean | 471.7 | 422.4 | 425.24 | 426.7 | 209.3 | A Rhesus + |
| GeoMean | 446 | 339.3 | 418.8 | 427.3 | 166.2 | B Rhesus + |
| GeoMean | 485 | 410.7 | 451.5 | 448 | 186.3 | O Rhesus + |
| Hct: 0.6% | ||||||
Mature Human Erythrocytes were treated with DMSO (0.2% (v/v), Bay 11–7082 (20 μM), parthenolide (50 μM) or dimethyl fumarate (DMF: 140 μM). Ionomycin (0.25 μM)-treated erythrocytes served as positive controls, and were first incubated in Ringer solution in the absence of ionomycin for 21.5 h. Subsequently, the cells were treated with ionomycin for 2.5 h.