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Pyramidal representation of white blood cell populations for determination of progressive multifocal leukoencephalopathy (PML) risk. The pyramid contains all white blood cell populations that can be counted in fumarate-treated patients to estimate their degree of immunosuppression. Low cell counts in higher layers are more indicative of PML risk, but they cannot be extrapolated accurately from the cell counts in the layers below. JCV = JC virus.
