Table 1.
Patient | Agent | Age/sex | Indication | Reaction | Reaction severitya | No. of desensitizations | Outcome |
---|---|---|---|---|---|---|---|
1 | Rituximab | 14/M | GLILD | 5th exposure | Severe | 4 | Successful |
2 | Rituximab | 7/M | PTLD | 4th exposure | Moderate | 3 | Successful |
3 | Rituximab | 23 months/F | OM | 1st exposure | Moderate | 10 | Successful |
Reexposure, reaction occurred after a previously tolerated course.
Brown classification criteria were used to classify reaction severity as mild, moderate, and severe.8
GLILD, granulomatous-lymphocytic interstitial lung disease; OM, opsoclonus myoclonus; PTLD, posttransplant lymphoproliferative disease.