Table 3.

Patient 3 - Rituximab Desensitization Protocol

Solution	Total volume (mL)	Drug per bag (mg)	Concentration (mg/mL)
1	250	2.06	0.008
2	250	20.6	0.082
3	250	205.189	0.821

Step	Solution	Rate (mL/h)	Rate (mg/kg/h)	Time (min)	Dose per step (mg)	Cumulative dose (mg)
1	1	1	0.0006	15	0.0021	0.0021
2	1	2.5	0.002	15	0.0052	0.0072
3	1	5	0.003	15	0.0103	0.0175
4	1	10	0.006	15	0.0206	0.0381
5	2	2.5	0.02	15	0.0515	0.0896
6	2	5	0.03	15	0.103	0.1926
7	2	10	0.07	15	0.206	0.3986
8	2	20	0.1	15	0.412	0.8106
9	3	5	0.3	15	1.0259	1.8366
10	3	10	0.7	15	2.0519	3.8885
11	3	20	1.3	15	4.1038	7.9922
12	3	30	2	482.5	198.0078	206

Total infusion time: 648 min. Final infusion rate: 2.0 mg/kg/h.