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. 2016 Jun 29;6:28934. doi: 10.1038/srep28934

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(a,b) The dextrorotatory (Dextro-) enantiomer (+)-(6R,9S)-JWU-A021 exerted a more powerful stimulatory effect in comparison to the levorotatory (Levo-) enantiomer (+)-(6S,9R)-JWU-A021 when it was tested in the fura-2 assay using monolayers of STC-1 cells. (c,d) Differential stimulation of an increase of [Ca²⁺]_i by the dextrorotatory, levorotatory, and racemic forms of either 1 μM or 0.3 μM JWU-A021. For all examples depicted here, the findings are representative of a single experiment that was repeated a minimum of three times on three different occasions with similar results.