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. 2016 Jun 29;36(26):7014–7026. doi: 10.1523/JNEUROSCI.0054-16.2016

Figure 8.

Figure 8.

Growth cone morphology and microtubule stability are altered in kbpst23 mutants. A, B, Growth cones of pLL axons in wild-type (A) and kbpst23 mutants (B) at 32 hpf. Yellow dotted line outlines the growth cone in each. C, D, Total number of processes extending from growth cones and the total growth cone area are reduced in kbpst23 mutants (ANOVA). E, Still of EB3-GFP transport from Movies 3. Asterisks indicate EB3-GFP-positive comets. F, G, Neither distance (ANOVA; p = 0.8287) nor velocity (ANOVA; p = 0.9367) of EB3 comets were altered in kbpst23 mutants. H, kbpst23 Mutants have increased microtubule stability in growth cones (p < 0.0001; F test; Tau: WT = 6.0, kbpst23 mutants = 18.7). Numbers on graphs indicate sample size. Error bars represent standard error of the mean. Scale bars, 10 μm.