Figure 1. TWEAK upregulates chemokine mRNA and protein expression in podocytes: differences in time-course.
Podocytes were treated with 100 ng/mL TWEAK. (A) Time-course of CCL21 mRNA induction. *p < 0.004 vs control. (B) Time-course of CCL19 mRNA induction. *p < 0.002 vs control. (C) Time-course of RANTES mRNA induction. *p < 0.003 vs control. Expression of mRNA was assessed by real time RT-PCR. Mean ± SEM of three independent experiments. (D) Representative Western blot of CCL21, CCL19 and RANTES protein in cell lysates.