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. Author manuscript; available in PMC: 2016 Jun 29.
Published in final edited form as: Diabetologia. 2010 Jul 15;53(11):2442–2451. doi: 10.1007/s00125-010-1837-2

Figure 2. RAGE KO provides superior renoprotection with diabetes than AT-2 receptor deficiency.

Figure 2

(A–B) Twenty four hour albumin excretion rates (AER) and (C–D) creatinine clearances were quantitated on plasma and urine samples collected from all mice with and without diabetes at study completion. AER and creatinine clearance were quantitated using ELISA and HPLC respectively. Since AER data was not normally distributed it is expressed as geometric mean ± tolerance factors. Values expressed as mean ± SD (n=10/group). WT – Wild Type, WT D – Wild Type Diabetic, RAGE KO – RAGE Knockout, AT-2R KO – Angiotensin II type 2 receptor Knockout.* p <0.05 vs WT, † p<0.05 vs AT-2 KO, ‡ p<0.05 vs WT D, § p < 0.05 vs RAGE KO D