Table 1.
Summary of mQTL (metabolite quantitative trait loci) and mGWAS (metabolome-based genome-wide association study) studies in plant.
| Species | Tissue | Population Type | Method | Metabolic Traits | Ref. |
|---|---|---|---|---|---|
| mQTL study | |||||
| Arabidopsis | Harvested seed | Recombinant inbred lines | HPLC | Tocopherol | [27] |
| Arabidopsis | Leaf | Recombinant inbred lines | GC–TOF-MS | Metabolome | [28] |
| Arabidopsis | Seed | Recombinant inbred lines | LC–MS | Flavinoids | [29] |
| Arabidopsis | Seedling | Recombinant inbred lines Introgression lines |
GC–TOF-MS | Metabolome | [21] |
| Brassica napus | Leaf Seed |
Doubled haploid lines | HPLC | Glucosinolates | [25] |
| Maize | Leaf | Recombinant inbred lines Natural accessions |
GC–TOF-MS | Primary Metabolites | [30] |
| Rice | Seed | Chromosomal segment substitution lines | LC-Q-TOF-MS | Metabolome | [24] |
| Rice | Seed | F2, F2-derived lines | GC–MS | Lipids | [31] |
| Rice | Flag leaf Germinating seed | Recombinant inbred lines | LC–EI–MS | Metabolome | [32] |
| Tomato | Fruit | Introgression lines | GC–MS | Metabolome | [22] |
| Tomato | Fruit | Introgression lines | GC–MS | Metabolome | [33] |
| Tomato | Fruit | Introgression lines | GC–MS, LC–MS | Metabolome | [34] |
| Tomato | Fruit | Introgression lines | GC–MS | Primary Metabolites | [35] |
| Tomato | Fruit | Introgression lines | UPLC | Secondary Metabolites | [36] |
| Wheat | Flag leaf | Doubled haploid lines | LC–ESI–MS | Metabolome | [23] |
| Wheat | Flag leaf | Doubled haploid lines | GC–MS | Metabolome | [37] |
| mGWAS study | |||||
| Arabidopsis | Seed | Natural accessions | LC–MS | Branched-chain amino acids | [38] |
| Arabidopsis | Leaf, Seedling | Natural accessions | LC–MS | Glucosinolates | [39] |
| Arabidopsis | Leaf | Natural accessions | GC–TOF-MS | Metabolome | [40] |
| Maize | Kernel | Natural accessions | UPLC–MS | Metabolome | [41] |
| Maize | Grain | Natural accessions | HPLC | Carotenoid | [42] |
| Maize | Grain | Natural accessions | HPLC | Tocochromanol | [43] |
| Maize | Leaf | Natural accessions | GC–MS | Metabolome | [44] |
| Maize | Leaf | Natural accessions | GC–MS | Metabolome | [45] |
| Maize | Kernel | Natural accessions | LC–MS | Metabolome | [46] |
| Potato | Tuber | Natural accessions | GC–MS | Primary Metabolites | [47] |
| Rice | Leaf | Natural accessions | LC–QTOF-MS | Secondary Metabolites | [48] |
| Rice | Leaf | Natural accessions | LC–MS | Metabolome | [49] |
| Rice | Leaf | Natural accessions | LC–MS | Phenolamides | [50] |
| Tomato | Fruit | Natural accessions | GC–MS | Metabolome | [51] |