Table 1.

Effect of the hormonal status on activity, kinetics, protein and mRNA levels of CACT and CiC.

Hormonal Status	Carrier	Activity	Km	Vmax	Protein	mRNA	References
Hyperthyroidism	CACT	+43%	↔	↑			[35]
Hypothyroidism	CACT	−41%	↔	↓			[36]
Hypothyroidism	CiC	−60%	↔	↓	−35%	−30%	[37]
Hyperthyroidism	CiC	+43%	↔	↑			[34]
Streptozotocin-induced diabetes (1–8 weeks)	CiC	−31% ÷ −51%					[49]
Streptozotocin-induced diabetes (3 weeks)	CiC	−35%	↔	↑	−37%	−35%	[48]

↔: no change; ↓: decrease; ↑: increase.