Table 2.

Meta-regression of moderators of constipation.

Moderator	Number of Studies	β	95% CI		p Value	R2
Mean age	30	0.0090	−0.0513	0.0693	0.7704	0.08
Percentage of males	31	0.0081	−0.0071	0.0233	0.2953	0
Percentage of smokers	8	0.0241	−0.0039	0.0522	0.0918	0
Clozapine mean dose	30	0.0017	−0.0004	0.0039	0.1085	0
Plasma clozapine	9	3.0455	−0.6171	6.708	0.1032	0.02
Plasma norclozapine	7	3.3561	−1.6898	8.4021	0.1924	0.01
Number of weeks clozapine treatment	28	0.0013	−0.0024	0.005	0.4888	0
% Sample schizophrenia	27	−0.0020	−0.0161	0.0121	0.7825	0
% Sample schizoaffective disorder	11	−0.0009	−0.0223	0.0204	0.9332	0