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Effects of SB203580 on TBI-induced long-term BM injury. Mice were treated with vehicle or SB203580 70 days after exposure to 6 Gy TBI, as described in the experimental section. BMNCs were collected from the mice 80 days after 6 Gy TBI. (A) The clonogenic function of HSCs was measured via a CAFC assay; (B) The clonogenic capacity of HSCs in BM was analyzed using a single-cell colony assay.
