Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jun 13;17(6):922. doi: 10.3390/ijms17060922

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Sphingosine, sphinganine and their phosphate derivatives during acute HCV infection. Sphingosine levels on follow-up were significantly upregulated in patients unable to clear HCV compared both to patients with spontaneous or subsequent therapy-induced resolution of HCV infection ((A), p = 0.02 and p = 0.013, respectively). Sphinganine levels were significantly elevated upon chronification of HCV infection on follow-up ((B), p = 0.006), while patients with subsequent SVR after antiviral treatment showed a significant longitudinal reduction of S1P levels ((C), ** p < 0.01). No significant difference in dhS1P levels was observed (D). Statistical significance between baseline and follow-up is indicated by asterisks (*). S1P: sphingosine 1 phosphate; dh: dihydro; SC: spontaneous clearance; SVR: sustained viral response; BSL: baseline; FU: follow-up; cHCV: chronic HCV.