Figure 8.

Influence of CHO cell migration by E-cadherin. Images were captured at 0 and 6 h time points for parental and N-glycosylated mutant CHO cell lines heterologously expressing E-cadherin, as indicated (A); rate of cell wound closure was determined for the various transfected CHO cell lines (B); cellular migratory rates in cell lines expressing E-cadherin were normalized to their respective non-transfected cell line (C). White lines at the leading edge of the cell monolayers, and the horizontal line connecting these two vertical lines represent the measured width of the cell wound. Asterisks indicate significant differences in mean values at a probability of p < 0.03 using one-way ANOVA with Bonferroni adjustments. Asterisk above line denotes significant differences in mean values at a probability of p < 0.03 using student t-test.