Table 1.
Frailty criteria and geriatric evaluation at baseline and post-treatment with Darmocare Pre® or placebo. * p < 0.05; ** p < 0.01.
| Variable | Baseline | Significance | Post-Treatment | Significance | ||
|---|---|---|---|---|---|---|
| Placebo Group (n = 22) |
Dermocare Pre® (n = 28) |
p Value | Placebo Group (n = 22) |
Dermocare Pre® (n = 28) |
p Value | |
| Exhaustion (score 0–3: 0 “never”; 1 “A few times” (1–2 days per week); 2 “Often” (3–4 days per week); or 3 “Most of the time” (almost each day)) | 1.1 ± 1.7 | 1.4 ± 1.7 | 0.74 | 1.7 ± 1.2 | 0.8 ± 1.4 ** | 0.002 |
| Slow walk (s) (time needed to walk 4.6 m) | 8.6 ± 9.0 | 8.4 ± 6.0 | 0.91 | 8.7 ± 4.2 | 7.9 ± 4.5 | 0.48 |
| Grip strength (right hand, kg) | 11.5 ± 5.7 | 10.6 ± 8.2 | 0.61 | 10.2 ± 4.1 | 12.4 ± 3.2 * | 0.04 |
| Grip strength (left hand, kg) | 10.2 ± 5.8 | 10.1 ± 7.6 | 0.92 | 9.1 ± 3.7 | 9.8 ± 3.5 | 0.50 |
| Self health-perception (score 0–10, being 0 the worst and 10 the best) | 7.1 ± 2.3 | 7.1 ± 2.1 | 0.96 | 6.8 ± 2.4 | 6.8 ± 2.0 | 0.96 |
| Body mass index | 26.1 ± 4.1 | 25.8 ± 4.2 | 0.97 | 26.0 ± 3.8 | 25.9 ± 4.1 | 0.96 |
| Athens insomnia scale | 3.4 ± 3.0 | 4.1 ± 4.7 | 0.77 | 4.5 ± 5.3 | 4.0 ± 4.3 | 0.68 |
| Barthel index | 76.2 ± 13.0 | 74.6 ± 17.7 | 0.69 | 78.3 ± 13.9 | 77.1 ± 29.9 | 0.87 |
| Mini–Mental state examination | 26.1 ± 2.2 | 26.5 ± 3.1 | 0.89 | 25.9 ± 2.1 | 26.4 ± 2.2 | 0.85 |