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Structures of kynurenine (62), (S)-(4-ethylsulfonyl) benzoylalanine hydrochloride ((S)-ESBA) (63) and its racemic mixture (64). The form of kynurenine that was used in designing inhibitors is highlighted by a polygon. The amino group, which plays a key role in stereoselectivity of ESBA in racemic mixtures is indicated by a circle.
