Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Depiction of the key molecular interactions between amino acid residues of the active site of hKAT-1 with (a) PHE (PDB code: 1W7M) and (b) IAC (PDB code: 3FVU) in the presence of LLP247 (PLP + LYS247). Both ligands form a hydrogen bond with ASN185 via their keto groups (green broken lines). A salt bridge interaction between ARG398 and the carboxylate moiety of both ligands is shown with red broken lines. All three-dimensional figures prepared using PyMOL [68].
