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The three-dimensional depiction of key molecular interactions between amino acids of the active site of hKAT-2 with PF-04859989 covalently bonded to PLP (cofactor) (indicated by a red circle); PDB code: 3UE8. PF-04859989 forms hydrogen bonds with ARG399A and ASN202A through its methoxy and hydroxyl moieties, shown with green broken lines.
