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The three-dimensional depiction of key molecular interactions between amino acid residues of the active site of mKAT-4 with KYN (PDB code: 3PD6). KYN forms hydrogen bonds with GLY65A, TYR160A and ASN215A via its amino and keto groups, (green broken lines). Salt bridge interactions between the ARG407A and the carboxylate moiety of KYN are shown with red broken lines.
