Table 5.
Drug | n | Median Dosage (mg/kg/day) | Median Length of Treatment (Days) | Side Effects (n) |
---|---|---|---|---|
Rifampicin | 415 | 17.5 | 240 | Itch, vomit and headache (1); rash (1); hypertransaminasemia (4) |
Pyrazinamide | 411 | 27 | 95 | Hypertransaminasemia (7); vomit and malaise (1); epigastric pain (1); hyperuricemia (5); drug induced hepatitis (1) |
Isoniazid | 396 | 10 | 242 | Drug induced hepatitis (1); hypertransaminasemia (4) |
Ethambutol | 245 | 17 | 86 | Vomit and malaise (1); neutropenia (1); drug induced hepatitis (1); epigastric pain (1) |
Streptomycin | 35 | 19 | 31 | |
Moxifloxacin | 31 | 10.3 | 161 | Tendinopathy (1); long QT syndrome (1) |
Linezolid | 17 | 19.1 | 108 | |
Amikacin | 12 | 16.8 | 24,5 | |
Cycloserine | 11 | 14.1 | 220 | |
Levofloxacin | 7 | 11.6 | 202 | |
PAS 1 | 6 | 118 | 172.5 | |
Ethionamide | 6 | 15.4 | 91.6 | |
Clarithromycin | 5 | 15.6 | 39.6 | |
Kanamicina | 1 | 10 | 142 | |
Ciprofloxacin | 4 | 17 | 238 | Vomit and weight loss (1) |
1 PAS: p-aminosalicylic acid.