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. 2016 Jun 21;17(6):980. doi: 10.3390/ijms17060980

Figure 1.

Figure 1

Peritumoral stromal cells express the melanoma-derived oncogenic BRAFV600E protein. (a,b) Tissue samples of a patient with BRAFV600E melanoma stained for the melanoma marker melanoma antigen recognized by T-cells (MART1) (red), the BRAFV600E mutant protein (brown) and hematoxylin (blue). Brown arrows indicate peritumoral MART1−/BRAFV600E+ cells displaying fibroblast (a) or macrophage (b) morphology. Blue arrows indicate MART1−/BRAFV600E− stromal cells (light blue from hematoxylin). Red lines indicate MART1+ melanoma cells. Black bars indicate 50 µm.