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. 2016 Jun 21;17(6):980. doi: 10.3390/ijms17060980

Figure 2.

Figure 2

Peritumoral stromal cells contain the melanoma-derived oncogenic BRAFV600E at the genomic level. (a) BRAFV600E melanoma tissue sample stained for MART1 (red), smooth muscle actin (SMA) (brown), and hematoxylin (blue) before (left panel) and after (right panel) laser-capture microdissection of MART1−/SMA+ fibroblasts (white line); (b,c) Tissue samples of BRAFV600E (b) primary melanoma and (c) melanoma metastasis stained for MART1 (red), CD68 (brown), and hematoxylin (blue) before (left panels) and after (right panels) laser-capture microdissection of MART1−/CD68+ macrophages (black line). Black bars indicate 150 µm.