Figure 3. . The combination of 25-(OH) vitamin D and non-HDL cholesterol values is a better predictor of chronic disease aggressiveness of cerebral cavernous malformation.

(A) Using 25-(OH) vitamin D values alone, AUC was 0.72 (95% CI: 0.57–0.88), compared with (B) AUC of 0.71 for non-HDL cholesterol levels (95% CI: 0.56–0.87). (C) Combination of the two biomarkers gave the higher AUC of 0.76 (95% CI: 0.62–0.91), suggesting a better prognostic value of chronic disease aggressiveness.

AUC: Area under the curve.