Fig. 3.

Principal component analysis and hierarchical clustering. (A) Principal component analysis of all patients analysed, evaluated based on their gene expression profiles. The first two principal components, consisting of two clusters of seven bladder pain syndrome (BPS) patients and seven controls, are circled in red. (B) Hierarchical clustering of differentially regulated genes of the seven BPS and seven control patients identified with the principal component analysis. Green denotes upregulated genes, whereas red denotes downregulated genes.

BPS = bladder pain syndrome.