Table 2.

Identification of Serum Biomarkers for Prediction of Schizophrenia Before Disease Onset

Molecular pathway	Analyte	Publication
Inflammation	Alpha-2 macroglobulin	Chan et al., 2015
	Beta-2 microglobulin	Chan et al., 2015
	Carcinoembryonic antigen	Chan et al., 2015
	Chemokine (C-C) motif ligand 8	Perkins et al., 2014
	Haptoglobin	Chan et al., 2015
	Immunoglobulin-A	Chan et al., 2015
	Immunoglobulin-E	Perkins et al., 2014
	Interleukin-1 receptor antagonist	Chan et al., 2015
	Interleukin-beta	Perkins et al., 2014
	Interleukin-10	Chan et al., 2015
	Interleukin-7	Perkins et al., 2014
	Interleukin-8	Perkins et al., 2014; Chan et al., 2015
	Interleukin-13	Chan et al., 2015
	Macrophage migration inhibitory factor	Chan et al., 2015
	Matrix metalloproteinase 7	Perkins et al., 2014
	Receptor for advanced glycosylation end products	Chan et al., 2015
	Serum glutamic oxaloacetic transaminase	Chan et al., 2015
	Tenascin C	Chan et al., 2015
	Uromodulin	Perkins et al., 2014
	Von Willebrand factor	Chan et al., 2015
Hormone signalling	Cortisol	Perkins et al., 2014
	Follicle-stimulating hormone	Chan et al., 2015
	Growth hormone	Perkins et al., 2014
	Leptin	Chan et al., 2015
	Pancreatic polypeptide	Chan et al., 2015
	Resistin	Chan et al., 2015
	Testosterone (total)	Chan et al., 2015
	Thyroid stimulating hormone	Perkins et al., 2014; Chan et al., 2015
Growth factor signalling	AXL receptor tyrosine kinase	Chan et al., 2015
	Insulin-like growth factor-binding protein 2	Chan et al., 2015
	Stem Cell Factor	Perkins et al. 2014; Chan et al., 2015
Clotting cascade	Angiotensin-converting enzyme	Chan et al., 2015
	Factor VII	Perkins et al., 2014; Chan et al., 2015
Lipid transport	Apolipoprotein-D	Perkins et al., 2014
	Malonaldehyde-modified low density lipoprotein	Perkins et al., 2014

The table shows the molecular pathways and specific molecules covered by these tests as well as the associated publications.