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. 2016 Apr 9;5:70–80. doi: 10.1016/j.bonr.2016.04.002

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 7 — Comparison of whole-body composition values determined using different scanners and voxel spacing. Cohort 1 mice were scanned at 2, 5 and 8 weeks of age on both the eXplore Locus Ultra and eXplore speCZT micro-CT scanners. Images were reconstructed to 154 μm for the eXplore Locus Ultra (green), and 150 μm and 100 μm for the eXplore speCZT (red and blue, respectively), and rescaled into Hounsfield units. Each voxel was then assigned as adipose, lean or skeletal tissue, and tissue masses were calculated. (A–F) illustrate parameters of whole-body composition in absolute values. (G–I) illustrate adipose, lean and skeletal tissue masses as a percentage of the CT-derived total body mass. Data are means ± S.D., n = 8 mice in each cohort. a indicates significant difference between the Ultra and speCZT 150 μm scans, b indicates significant difference between the Ultra and speCZT 100 μm scans, and c indicates significant difference between the speCZT 150 μm and speCZT 100 μm scans (p < 0.05, determined by two-way repeated measures ANOVA with Bonferroni's post hoc test). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)